Analyzing intact chromatin empowers our understanding of transcriptional regulation by proteins, methylation, acetylation, and other DNA modifications.

Epigenomics

Use NGS to probe modifications and regulations of the genome

NGS Epigenomic Services

ChIP-Seq

Use Chromatin Immunoprecipitation Sequencing (ChIP-seq) to gain intricate knowledge on regulators and explore targeted therapy development.

  • Scalable high throughput capability operating in CLIA-lab

  • Mature bioinformatics pipelines

  • Reduced bias with KAPA Hyper Prep

CUT&RUN

Study epigenetic regulation and analyze the protein interactions with DNA. This technology isolates protein-DNA complexes of interest and can handle a low number of cells to reduce non-specific signals in data.

  • Optimized protocol for higher-resolution data

  • Quick turnaround

  • Scalable high throughput capability on Illumina platforms

WGBS

Genome-wide profiling of DNA methylation sites provides insight into epigenomic mapping, patterns of epigenetic markers, aberrant methylation, and more.

  • Optimized workflow for varying sample input

  • Superior data quality

  • Expert technical and bioinformatic support including QC, Mapping, Duplicate Removal, CpG and Non-CpG Differential Methylation Analysis, and more

ATAC-Seq

Genome-wide landscaping with Assay for Transposase-Accessible Chromatin sequencing (ATAC-seq) using a small starting input.

  • Reliable technical support for successful outcomes

  • Mature bioinformatic pipeline and continuous support after project completion

RRBS

RRBS is an alternative method to studying methylated sites which utilize restriction enzymes unaffected by methylation.

  • Optimized workflow for varying sample input

  • Reduced cost compared to that of WGBS

  • Expert technical and project management support

  • Bioinformatic support including QC, Mapping, Duplicate Removal, CpG and Non-CpG Differential Methylation Analysis.

Hi-C Assay

High Throughput Chromosome Conformation Capture (Hi-C) Assay studies chromosomal interactions. Hi-C can identify genome-wide unbiased long-range interactions, and reveal chromosomal interactions.

  • Stringent QC steps to reduce non-specific interchromosomal contacts, improve on-target capture

  • Expert technical, project management, and bioinformatic support

Advantages of Working with Admera Health

Expert Scientific Support

Experienced technical support team with a solution-oriented mindset

High-Throughput Capabilities

Robust workflows to support high volume and high data throughput

High Data Quality

Improved workflows and quality steps to ensure superior data quality

Other NGS Services That May Be of Interest

Admera Health’s dedicated team of expert bioinformaticians offer comprehensive data analysis services covering genomics, metagenomics, transcriptomics, and epigenomics.

Bioinformatics

Admera Health provides individualized attention for DNA sequencing projects.

Genomics

Admera Health offers exceptional RNA-seq services with flexibility and capability for high-throughput according to customers’ needs.

Transcriptomic