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Genetics for Smarter Medication Management

PGxOne™ Plus is a 60+ gene pharmacogenomics (PGx) test that provides insight into how patients may respond to certain medications based on DNA variants that affect pharmacokinetics and pharmacodynamics. Using Next-Generation molecular biology technologies, the test provides results aligning with FDA sources and guidelines from professional organizations.1,2

be8fda7f-53fd-4231-ad5f-1500bf86dcce PGxOne™ Plus
f2726b9d-243a-4bfa-b849-4a44598967d9 PGxOne™ Plus
2797943f-219f-424e-8f07-bd570f67c057 PGxOne™ Plus
PGxOnePlus_RxVision_logo_WHITE_FINAL PGxOne™ Plus


Genetics for Smarter Medication Management

PGxOne™ Plus is a 60+ gene pharmacogenomics (PGx) test that provides insight into how patients may respond to certain medications based on DNA variants that affect pharmacokinetics and pharmacodynamics. Using Next-Generation molecular biology technologies, the test provides results aligning with FDA sources and guidelines from professional organizations.1,2

be8fda7f-53fd-4231-ad5f-1500bf86dcce PGxOne™ Plus
f2726b9d-243a-4bfa-b849-4a44598967d9 PGxOne™ Plus
2797943f-219f-424e-8f07-bd570f67c057 PGxOne™ Plus

PGxOne™ Plus provides an additional tool for making informed drug management decisions with the goal of reducing adverse drug reactions and trial-and-error dosing and drug selection.

Reasons to order pharmacogenomics testing:

            • When the FDA requires/recommends pharmacogenomics (PGx) testing for a medication
            • When the patient has had a severe adverse drug reaction(s) or complications due to medications
            • There is a family history of a serious adverse drug reaction or known pharmacogenomic variant
            • Identifying patients who require a higher or lower-than–standard dose of a medication
            • When patients have experienced multiple treatment failures
            • The recommended drug dosage has not relieved symptoms or the patient has sensitivity to a medication
            • When a patient is experiencing unexpected or exaggerated response(s) to a medication(s)
            • To improve a patient’s medication compliance/adherence
            • For patients who are on multiple medications
            • PGx testing can be taken preemptively so the results can be readily available when needed
              *References Available

Pharmacogenomics helps to reduce unfavorable outcomes in patients infected with COVID-19 with underlying high-risk medical conditions. 

4a180cf0-a85d-424b-b936-4db97aec47ce PGxOne™ Plus

Gene-Drug Interactions in the form of Clear, Color-Coded Medically Actionable Results

Consider-Alt-Icon PGxOne™ Plus

Consider Alternatives: refers to gene-drug pairs in which the interaction between a drug and one or several genes may result in a clinically severe and potentially deadly adverse drug reaction(s) and lack of efficacy. Most medications included in this gene-drug pair category still can be used. However, extreme caution and clinical judgment should be exercised. Providers should share the corresponding gene-drug interaction with their patients and follow FDA recommendations.

Caution-Icon PGxOne™ Plus

Use with Caution: refers to gene-drug pairs in which the interaction between a drug and one or several genes may result in a mild adverse drug reaction(s) and lack of efficacy. Most medications included in this gene-drug pair category still can be used. However, caution and clinical judgment should be exercised. Providers should share the corresponding gene-drug interaction with their patients and follow FDA recommendations.

Drug-Management-Icon PGxOne™ Plus

Drug Management: refers to gene-drug pairs in which a negative drug response (adverse drug reaction(s) and lack of efficacy) might be preventable by adjusting the medication to the patient’s individual needs based on pharmacogenomic results and any other non-genetic factors of your knowledge. Providers should exercise caution and clinical judgment, share the corresponding gene-drug interaction their patients, and follow FDA recommendations.

Norml-Response-Icon PGxOne™ Plus

Normal Response Expected: refers to gene-drug pairs in which the corresponding drug response (adverse drug reaction(s) risk and efficacy) shall correlate with the FDA label description and is like that of the general population. Keep in mind that all drugs come with associated risks and should be taken into consideration when prescribing any medication. Providers should exercise caution and clinical judgment, share the corresponding gene-drug interaction their patients, and follow FDA recommendations.

PGxOne™ Plus provides an additional tool for making informed drug management decisions with the goal of reducing adverse drug reactions and trial-and-error dosing and drug selection.

Reasons to order pharmacogenomics testing:

      • When the FDA requires/recommends pharmacogenomics (PGx) testing for a medication
      • When the patient has had a severe adverse drug reaction(s) or complications due to medications
      • There is a family history of a serious adverse drug reaction or known pharmacogenomic variant
      • Identifying patients who require a higher or lower-than–standard dose of a medication
      • When patients have experienced multiple treatment failures
      • The recommended drug dosage has not relieved symptoms or the patient has sensitivity to a medication
      • When a patient is experiencing unexpected or exaggerated response(s) to a medication(s)
      • To improve a patient’s medication compliance/adherence
      • For patients who are on multiple medications
      • PGx testing can be taken preemptively so the results can be readily available when needed
        *References Available

Pharmacogenomics helps to reduce unfavorable outcomes in patients infected with COVID-19 with underlying high-risk medical conditions. 

4a180cf0-a85d-424b-b936-4db97aec47ce PGxOne™ Plus

Gene-Drug Interactions in the form of Clear, Color-Coded Medically Actionable Results

Consider-Alt-Icon PGxOne™ Plus

Consider Alternatives: refers to gene-drug pairs in which the interaction between a drug and one or several genes may result in a clinically severe and potentially deadly adverse drug reaction(s) and lack of efficacy. Most medications included in this gene-drug pair category still can be used. However, extreme caution and clinical judgment should be exercised. Providers should share the corresponding gene-drug interaction with their patients and follow FDA recommendations.

Caution-Icon PGxOne™ Plus

Use with Caution: refers to gene-drug pairs in which the interaction between a drug and one or several genes may result in a mild adverse drug reaction(s) and lack of efficacy. Most medications included in this gene-drug pair category still can be used. However, caution and clinical judgment should be exercised. Providers should share the corresponding gene-drug interaction with their patients and follow FDA recommendations.

Drug-Management-Icon PGxOne™ Plus

Drug Management: refers to gene-drug pairs in which a negative drug response (adverse drug reaction(s) and lack of efficacy) might be preventable by adjusting the medication to the patient’s individual needs based on pharmacogenomic results and any other non-genetic factors of your knowledge. Providers should exercise caution and clinical judgment, share the corresponding gene-drug interaction their patients, and follow FDA recommendations.

Norml-Response-Icon PGxOne™ Plus

Normal Response Expected: refers to gene-drug pairs in which the corresponding drug response (adverse drug reaction(s) risk and efficacy) shall correlate with the FDA label description and is like that of the general population. Keep in mind that all drugs come with associated risks and should be taken into consideration when prescribing any medication. Providers should exercise caution and clinical judgment, share the corresponding gene-drug interaction their patients, and follow FDA recommendations.

Actionable Reports

Easy to read reports with gene-drug interactions aligning with the FDA’s latest recommendations

31f22183-9e77-48f4-8f35-9bc2c4313911 PGxOne™ Plus

Search by Drug, Therapeutic Area, or Drug Class

PGxOne™ Plus provides gene-drug interactions for an extensive range of medications used widely in psychiatry, cardiology, pain management, oncology, and multiple other clinical specialties.

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Admera Health’s dynamic online reporting tool pairs the PGxOne™ Pus test to provide a complete PGx assessment.

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Sample Collection

This video, produced by DNA Genotek, walks you through the process for proper sample collection. This will reduce the need for resampling and yield accurate test results.

Sample Collection

This video, produced by DNA Genotek, walks you through the process for proper sample collection. This will reduce the need for resampling and yield accurate test results.